Abasy (Across-bacteria systems) Atlas contains the most comprehensive collection of reconstructed and meta-curated bacterial gene regulatory networks having enough quality to allow system-level analyses. It features predictions of systems and system-level elements (global regulators, basal machinery genes, modular genes, and intermodular genes) and statistical and structural properties for 102 networks (338,001 regulatory interactions) covering 42 bacteria (64% Gram positive and 36% Gram negative) distributed in 10 species (Mycobacterium tuberculosis, Bacillus subtilis, Corynebacterium glutamicum, Escherichia coli, Streptomyces coelicolor, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, and Pseudomonas paraeruginosa), containing 13,742 regulons and 7,193 systems (modules).
According to Wikipedia: The Abasy are demons in the mythology of the Sakha (also known as the Yakuts). Yakut Shamanism divides the universe into upper and lower layers, with the earth being a kind of indeterminate space or matter in between. The Abasy occupy the lower level, referred to as the underworld or kingdom of darkness.
The natural decomposition approach also divides a regulatory network into three layers: coordination, processing, and integration. The lower layer is populated by the intermodular genes, a class of genes first identified by the natural decomposition approach, which integrate signals coming from different systems eliciting complex combinatorial responses[2].
Abasy Atlas is actively developed by the Regulatory Systems Biology Research Group at the Program of Systems Biology, Center for Genomic Sciences (CCG), UNAM.
