Abasy Atlas v2.2

A comprehensive atlas of regulatory networks and their systems, global structural properties, and system-level elements

Abasy (Across-bacteria systems) Atlas contains the most comprehensive collection of reconstructed and meta-curated bacterial gene regulatory networks having enough quality to allow system-level analyses. It features predictions of systems and system-level elements (global regulators, basal machinery genes, modular genes, and intermodular genes) and statistical and structural properties for 76 networks (204,282 regulatory interactions) covering 42 bacteria (64% Gram positive and 36% Gram negative) distributed in 9 species (Mycobacterium tuberculosis, Bacillus subtilis, Escherichia coli, Corynebacterium glutamicum, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus pneumoniae, and Streptomyces coelicolor), containing 8,459 regulons and 4,335 systems (modules).

According to Wikipedia: The Abasy are demons in the mythology of the Sakha (also known as the Yakuts). Yakut Shamanism divides the universe into upper and lower layers, with the earth being a kind of indeterminate space or matter in between. The Abasy occupy the lower level, referred to as the underworld or kingdom of darkness. The natural decomposition approach also divides a regulatory network into three layers: coordination, processing, and integration. The lower layer is populated by the intermodular genes, a class of genes first identified by the natural decomposition approach, which integrate signals coming from different systems eliciting complex combinatorial responses[2].

Abasy Atlas is actively developed by the Regulatory Systems Biology Research Group at the Laboratory of Systems and Synthetic Biology, Center for Genomic Sciences (CCG), UNAM.

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