Abasy Atlas v2.2

A comprehensive atlas of regulatory networks and their systems, global structural properties, and system-level elements

Abasy (Across-bacteria systems) Atlas contains the most comprehensive collection of reconstructed and meta-curated bacterial gene regulatory networks having enough quality to allow system-level analyses. It features predictions of systems and system-level elements (global regulators, basal machinery genes, modular genes, and intermodular genes) and statistical and structural properties for 76 networks (204,282 regulatory interactions) covering 42 bacteria (64% Gram positive and 36% Gram negative) distributed in 9 species (Mycobacterium tuberculosis, Bacillus subtilis, Escherichia coli, Corynebacterium glutamicum, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus pneumoniae, and Streptomyces coelicolor), containing 8,459 regulons and 4,335 systems (modules).

According to Wikipedia: The Abasy are demons in the mythology of the Sakha (also known as the Yakuts). Yakut Shamanism divides the universe into upper and lower layers, with the earth being a kind of indeterminate space or matter in between. The Abasy occupy the lower level, referred to as the underworld or kingdom of darkness. The natural decomposition approach also divides a regulatory network into three layers: coordination, processing, and integration. The lower layer is populated by the intermodular genes, a class of genes first identified by the natural decomposition approach, which integrate signals coming from different systems eliciting complex combinatorial responses[2].

Abasy Atlas is actively developed by the Regulatory Systems Biology Research Group at the Laboratory of Systems and Synthetic Biology, Center for Genomic Sciences (CCG), UNAM.

NEWS

  • Abasy will be down from December 10 16:00 CDT to December 11 14:00 CDT as servers and no-breaks will be under maintenaince, sorry for the incovenience (10/Dec/19)
  • Abasy v2.2 has been publicly released today! (19/jun/19)
  • Paper on complexity, completeness and quality of regulatory networks 10.1038/s41598-019-39866-z (06/Mar/19)
  • Abasy v2.0 has been publicly released today! (20/ago/18)
  • Paper on C. glutamicum new data 10.1016/j.jbiotec.2016.10.025 (06/Nov/16)
  • Paper on Abasy Atlas v1.0 10.1093/database/baw089 (05/May/16)
  • First public release v1.0! (30/Mar/16)