Abasy Atlas v2.9

A comprehensive atlas of regulomes and their systems, global structural properties, and system-level elements

Abasy (Across-bacteria systems) Atlas contains the most comprehensive collection of reconstructed and meta-curated bacterial gene regulatory networks having enough quality to allow system-level analyses. It features predictions of systems and system-level elements (global regulators, basal machinery genes, modular genes, and intermodular genes) and statistical and structural properties for 102 networks (338,001 regulatory interactions) covering 42 bacteria (64% Gram positive and 36% Gram negative) distributed in 9 species (Mycobacterium tuberculosis, Bacillus subtilis, Corynebacterium glutamicum, Escherichia coli, Streptomyces coelicolor, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae), containing 13,742 regulons and 7,193 systems (modules).

According to Wikipedia: The Abasy are demons in the mythology of the Sakha (also known as the Yakuts). Yakut Shamanism divides the universe into upper and lower layers, with the earth being a kind of indeterminate space or matter in between. The Abasy occupy the lower level, referred to as the underworld or kingdom of darkness. The natural decomposition approach also divides a regulatory network into three layers: coordination, processing, and integration. The lower layer is populated by the intermodular genes, a class of genes first identified by the natural decomposition approach, which integrate signals coming from different systems eliciting complex combinatorial responses[2].

Abasy Atlas is actively developed by the Regulatory Systems Biology Research Group at the Program of Systems Biology, Center for Genomic Sciences (CCG), UNAM.

NEWS

    Abasy could have intermittent interruptions on March 02 from 15:00 to 17:00 CST as campus data services will be under maintenaince, sorry for the incovenience (26/Feb/26)
  • Abasy v2.9 has been publicly released today! (06/Jun/24)
  • Paper on the relevance of gene regulatory network structure to improve network inference 10.3389/fgene.2023.1143382 (16/Feb/23)
  • Abasy v2.8 has been publicly released today! (12/Oct/22)
  • Paper on system principles governing regulatory networks architecture 10.3389/fbioe.2022.888732 (12/May/22)
  • Paper on S. coelicolor new curated data 10.1038/s41598-022-06658-x (18/Feb/22)
  • Abasy v2.5 has been publicly released today! (01/Sep/21)
  • Paper on C. glutamicum new curated data: beyond transcription 10.3390/microorganisms9071395 (12/Jan/21)
  • Abasy v2.4 has been publicly released today! (14/Dec/20)
  • Paper on Abasy Atlas v2.2 10.1016/j.csbj.2020.05.015 (15/May/20)