Abasy Atlas v2.9

A comprehensive atlas of regulomes and their systems, global structural properties, and system-level elements

Abasy (Across-bacteria systems) Atlas contains the most comprehensive collection of reconstructed and meta-curated bacterial gene regulatory networks having enough quality to allow system-level analyses. It features predictions of systems and system-level elements (global regulators, basal machinery genes, modular genes, and intermodular genes) and statistical and structural properties for 102 networks (338,001 regulatory interactions) covering 42 bacteria (64% Gram positive and 36% Gram negative) distributed in 9 species (Mycobacterium tuberculosis, Bacillus subtilis, Corynebacterium glutamicum, Escherichia coli, Streptomyces coelicolor, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae), containing 13,742 regulons and 7,193 systems (modules).

According to Wikipedia: The Abasy are demons in the mythology of the Sakha (also known as the Yakuts). Yakut Shamanism divides the universe into upper and lower layers, with the earth being a kind of indeterminate space or matter in between. The Abasy occupy the lower level, referred to as the underworld or kingdom of darkness. The natural decomposition approach also divides a regulatory network into three layers: coordination, processing, and integration. The lower layer is populated by the intermodular genes, a class of genes first identified by the natural decomposition approach, which integrate signals coming from different systems eliciting complex combinatorial responses[2].

Abasy Atlas is actively developed by the Regulatory Systems Biology Research Group at the Program of Systems Biology, Center for Genomic Sciences (CCG), UNAM.

NEWS

  • Abasy v2.9 has been publicly released today! (06/Jun/24)
  • Paper on the relevance of gene regulatory network structure to improve network inference 10.3389/fgene.2023.1143382 (16/Feb/23)
  • Abasy v2.8 has been publicly released today! (12/Oct/22)
  • Paper on system principles governing regulatory networks architecture 10.3389/fbioe.2022.888732 (12/May/22)
  • Paper on S. coelicolor new curated data 10.1038/s41598-022-06658-x (18/Feb/22)
  • Abasy v2.5 has been publicly released today! (01/Sep/21)
  • Paper on C. glutamicum new curated data: beyond transcription 10.3390/microorganisms9071395 (12/Jan/21)
  • Abasy v2.4 has been publicly released today! (14/Dec/20)
  • Paper on Abasy Atlas v2.2 10.1016/j.csbj.2020.05.015 (15/May/20)