Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [2016, 11-12-15, Weak + Strong]
kgd – Basal machinerykout: 0, kin: 4, Clustering: 0.5
Locus tag–Rv1248c
UniProt ID–P9WIS5
NCBI GeneID–887084
Synonyms–RVBD_1248c
Biological function
Product function–multifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase
GO terms
GO:0000287–Magnesium ion binding
GO:0004149–Dihydrolipoyllysine-residue succinyltransferase activity
GO:0005618–Cell wall
GO:0005886–Plasma membrane
GO:0006099–Tricarboxylic acid cycle
GO:0006103–2-oxoglutarate metabolic process
GO:0008683–2-oxoglutarate decarboxylase activity
GO:0009055–Electron carrier activity
GO:0016624–Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0030976–Thiamine pyrophosphate binding
GO:0040007–Growth
GO:0045254–Pyruvate dehydrogenase complex
GO:0050439–2-hydroxy-3-oxoadipate synthase activity
GO:0055114–Oxidation-reduction process
COGs
COG0508–Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes (C)
COG0567–2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes (C)
kgd – Neighborhood
    Global regulators  Intermodulars  Weak interactions  Disconnected nodes  Interaction tooltips  | Layout:  Animate | Flash:  | Selection mode