Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [2016, 11-12-15, Weak + Strong]
esxA – Basal machinerykout: 0, kin: 7, Clustering: 0.2381
Locus tagRv3875
UniProt IDP9WNK7
NCBI GeneID886209
SynonymsRVBD_3875, esaT6
Biological function
Product functionESAT-6 protein EsxA
GO terms
GO:0005576Extracellular region
GO:0005618Cell wall
GO:0005737Cytoplasm
GO:0005886Plasma membrane
GO:0009405Pathogenesis
GO:0042803Protein homodimerization activity
GO:0044315Protein secretion by the type VII secretion system
GO:0046812Host cell surface binding
GO:0052027Modulation by symbiont of host signal transduction pathway
GO:0052083Negative regulation by symbiont of host cell-mediated immune response
COGs
COG4842Uncharacterized protein conserved in bacteria (S)
esxA – Neighborhood
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