Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [2016, 11-12-15, Weak + Strong]
dosT – Basal machinerykout: 0, kin: 2, Clustering: 1
Locus tagRv2027c
UniProt IDP9WGK1
NCBI GeneID888471
SynonymsRVBD_2027c
Biological function
Product functiontwo component sensor histidine kinase DosT
GO terms
GO:0000155Phosphorelay sensor kinase activity
GO:0000287Magnesium ion binding
GO:0004672Protein kinase activity
GO:0004673Protein histidine kinase activity
GO:0005509Calcium ion binding
GO:0005524ATP binding
GO:0005737Cytoplasm
GO:0016021Integral component of membrane
GO:0018106Peptidyl-histidine phosphorylation
GO:0019825Oxygen binding
GO:0019826Oxygen sensor activity
GO:0020037Heme binding
GO:0046777Protein autophosphorylation
GO:0070025Carbon monoxide binding
GO:0070026Nitric oxide binding
GO:0070483Detection of hypoxia
COGs
COG2203FOG: GAF domain (T)
COG4585Signal transduction histidine kinase (T)
dosT – Neighborhood
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