| Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [2015, 15, Weak + Strong] |
|---|
| topA – Intermodular | kout: 0, kin: 4, Clustering: 0.16667 | |
|---|---|---|
| Locus tag | – | Rv3646c |
| UniProt ID | – | P9WG49 |
| NCBI GeneID | – | 885608 |
| Synonyms | – | RVBD_3646c |
| Biological function | ||
| Product function | – | DNA topoisomerase I |
| GO terms | ||
| GO:0000287 | – | Magnesium ion binding |
| GO:0003677 | – | DNA binding |
| GO:0003917 | – | DNA topoisomerase type I activity |
| GO:0005618 | – | Cell wall |
| GO:0005829 | – | Cytosol |
| GO:0005886 | – | Plasma membrane |
| GO:0006265 | – | DNA topological change |
| GO:0040007 | – | Growth |
| GO:0060701 | – | Negative regulation of ribonuclease activity |
| COGs | ||
| COG0550 | – | Topoisomerase IA (L) |
| COG1754 | – | Uncharacterized C-terminal domain of topoisomerase IA (R) |
| topA – Neighborhood | ||