Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [2015, 15, Weak + Strong]
kgd – Basal machinerykout: 0, kin: 3, Clustering: 0.66667
Locus tagRv1248c
UniProt IDP9WIS5
NCBI GeneID887084
SynonymsRVBD_1248c
Biological function
Product functionmultifunctional 2-oxoglutarate dehydrogenase E1 component /2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase
GO terms
GO:0000287Magnesium ion binding
GO:0004149Dihydrolipoyllysine-residue succinyltransferase activity
GO:0005618Cell wall
GO:0005886Plasma membrane
GO:0006099Tricarboxylic acid cycle
GO:00061032-oxoglutarate metabolic process
GO:00086832-oxoglutarate decarboxylase activity
GO:0009055Electron carrier activity
GO:0016624Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0030976Thiamine pyrophosphate binding
GO:0040007Growth
GO:0045254Pyruvate dehydrogenase complex
GO:00504392-hydroxy-3-oxoadipate synthase activity
GO:0055114Oxidation-reduction process
COGs
COG0508Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes (C)
COG05672-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes (C)
kgd – Neighborhood
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