Escherichia coli str. K-12 substr. MG1655 [2020, RDB18-13, Strong]
putAModule 39.1 (graph)kout: 2, kin: 3, Clustering: 0.33333
Locus tagb1014
UniProt IDP09546
NCBI GeneID945600
SynonymspoaA, JW0999
Biological function
Product functionfused PutA transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase
GO terms
GO:0000986Bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding
GO:0001141Bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677DNA binding
GO:00038421-pyrroline-5-carboxylate dehydrogenase activity
GO:0004029Aldehyde dehydrogenase (NAD) activity
GO:0004657Proline dehydrogenase activity
GO:0006561Proline biosynthetic process
GO:0009898Cytoplasmic side of plasma membrane
GO:0010133Proline catabolic process to glutamate
GO:0043565Sequence-specific DNA binding
GO:0045892Negative regulation of transcription, DNA-templated
GO:0050660Flavin adenine dinucleotide binding
COGs
COG0506Proline dehydrogenase (E)
COG4230Delta 1-pyrroline-5-carboxylate dehydrogenase (C)
putA – Neighborhood
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