Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (2015)

Modular genes
Gene Product description NDA class
acg NAD(P)H nitroreductase acg 1.5
ald L-alanine dehydrogenase 1.2
argC N-acetyl-gamma-glutamyl-phoshate reductase 25
argR arginine repressor 25
atpA ATP synthase subunit alpha 1.36
atsA arylsulfatase AtsA 1.9
bioF2 8-amino-7-oxononanoate synthase 1.1
blaI transcriptional repressor BlaI 1.1
celA2a -- 1.27
clgR transcriptional regulator ClgR 1.5
clpB chaperone protein ClpB 12
cmr HTH-type transcriptional regulator Cmr 11
crp cAMP receptor protein 1.10
ctaB protoheme IX farnesyltransferase 1.1
ctpB cation-transporter P-type ATPase B 1.1
ctpJ cation transporter ATPase J 26
cydA cytochrome D ubiquinol oxidase subunit I CydA 1.1
cyp125 steroid C26-monooxygenase 9
cyp138 cytochrome P450 Cyp138 1.36
cysA1 -- 1.16
cysD sulfate adenylyltransferase subunit 2 23
cysO sulfur carrier protein CysO 1.36
desA1 acyl-ACP desaturase DesA 1.26
desA2 acyl-ACP desaturase DesA 1.26
desA3 stearoyl-CoA 9-desaturase 13
dnaK chaperone protein DnaK 12
eccA3 ESX-3 secretion system protein EccA 4
echA11 enoyl-CoA hydratase EchA11 2
echA20 enoyl-CoA hydratase EchA20 1.24
espB ESX-1 secretion-associated protein EspB 1.32
etfB electron transfer flavoprotein subunit beta 7
fabG short-chain type dehydrogenase/reductase 7
fadA2 acetyl-CoA acetyltransferase FadA 7
fadA5 acetyl-CoA acetyltransferase FadA 9
fadD3 fatty-acid--CoA ligase FadD3 1.24
fadD35 fatty-acid--CoA ligase FadD35 6
fadD4 fatty-acid--CoA ligase FadD4 1.38
fadE24 acyl-CoA dehydrogenase FadE24 7
fadE30 acyl-CoA dehydrogenase FadE30 1.24
fadE34 acyl-CoA dehydrogenase FadE34 13
fadE8 acyl-CoA dehydrogenase FadE8 27
fbpA diacylglycerol acyltransferase/mycolyltransferase Ag85A 1.29
ftsZ cell division protein FtsZ 2
gca GDP-mannose 4,6-dehydratase 2
groS chaperonin GroES 1.31
hbhA heparin binding hemagglutinin HbhA 1.27
hemL glutamate-1-semialdehyde 2,1-aminomutase 1.1
higA3 transcriptional regulator 30
higB3 hypothetical protein 30
hmp 3-ketosteroid-9-alpha-hydroxylase reductase subunit 9
hrcA heat-inducible transcription repressor HrcA 1.31
hsaA flavin-dependent monooxygenase oxygenase subunit HsaA 9
hspR heat shock protein transcriptional repressor HspR 12
hspX alpha-crystallin 1.5
iniB isoniazid inducible protein IniB 3
ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1.7
kasA 3-oxoacyl-ACP synthase 1 1.19
kmtR HTH-type transcriptional regulator KmtR 5
kstR2 HTH-type transcriptional regulator KstR2 1.24
lat L-lysine-epsilon aminotransferase 1.2
lipX lipase LipX 1.9
lppW alanine-rich lipoprotein LppW 1.35
lpqQ lipoprotein LpqQ 21
lrpA transcriptional regulator LrpA 1.2
mazE6 antitoxin MazE6 1.8
mesT epoxide hydrolase MesT 1.29
mmpL6 transmembrane transport protein MmpL6 1.36
mmpS4 membrane protein MmpS4 1.10
moaR1 transcriptional regulator MoaR 1.1
moeW molybdopterin biosynthesis protein MoeW 1.11
moeZ adenylyltransferase/sulfurtransferase 1.36
mprA two-component response regulator MrpA 10
mshB 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 1.9
mycP4 membrane-anchored mycosin 8
mymA FAD-containing monooxygenase MymA 29
nadR transcriptional regulator NadR 1.19
nirB nitrite reductase large subunit NirB 12
nmtR HTH-type transcriptional regulator NmtR 26
nrdF1 ribonucleoside-diphosphate reductase subunit beta NrdF1 1.25
oxyS oxidative stress response regulatory protein OxyS 1.20
panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 3
papA4 polyketide synthase associated protein PapA 1.16
PE15 PE family protein PE15 4
PE25 PE family protein PE25 10
PE31 PE family protein PE31 2
PE35 PE family protein PE35 1.32
pepN aminopeptidase PepN 1.16
PE_PGRS38 PE-PGRS family protein PE_PGRS38 5
PE_PGRS61 PE-PGRS family-related protein PE_PGRS61 3
pflA pyruvate formate lyase activating protein PflA 7
pks3 polyketide beta-ketoacyl synthase 1.31
ppe1 PPE family protein PPE1 1.1
PPE18 PPE family protein PPE18 10
ppe3 PPE family protein PPE3 4
PPE43 PPE family protein PPE43 8
ppe44 PPE family protein PPE44 1.35
PPE56 PPE family protein PPE56 3
ppe57 PPE family protein PPE57 1.8
ppe59 PPE family protein PPE59 6
ppe61 PPE family protein PPE61 9
ppe66 PPE family protein PPE66 2
ppiB peptidyl-prolyl cis-trans isomerase B 19
proX glycine betaine/carnitine/choline/L-proline ABC transporter substrate-binding lipoprotein ProX 1.18
proZ glycine betaine/carnitine/choline/L-proline ABC transporter permease ProZ 6
pyrR bifunctional pyrimidine operon regulatory protein/uracil phosphoribosyltransferase 1.33
rmlB dTDP-glucose 4,6-dehydratase 16
rocA pyrroline-5-carboxylate dehydrogenase RocA 17
rpmB2 50S ribosomal protein L28 4
rpmD 50S ribosomal protein L30 1.15
rpmJ 50S ribosomal protein L36 14
rpsB 30S ribosomal protein S2 2
rpsD 30S ribosomal protein S4 3
rpsM 30S ribosomal protein S13 14
rsbW anti-sigma factor RsbW 1.38
rsmA anti-sigma-M factor RsmA 1.35
Rv0042c transcriptional regulator 2
Rv0043c HTH-type transcriptional regulator 1.18
Rv0067c transcriptional regulator 1.17
Rv0068 oxidoreductase 1.17
Rv0076c membrane protein 1.21
Rv0077c oxidoreductase 22
Rv0078 transcriptional regulator 22
Rv0089 methyltransferase 8
Rv0094c hypothetical protein 3
Rv0095c hypothetical protein 1.34
Rv0097 oxidoreductase 1.1
Rv0104 hypothetical protein 1.10
Rv0106 hypothetical protein 4
Rv0158 transcriptional regulator 1.39
Rv0188 transmembrane protein 8
Rv0191 MFS-type transporter 1.21
Rv0194 multidrug ABC transporter ATPase/permease 1.21
Rv0195 two component transcriptional regulator 1.21
Rv0213c methyltransferase 1.38
Rv0219 transmembrane protein 1.34
Rv0232 transcriptional regulator 1.3
Rv0238 transcriptional regulator 7
Rv0275c transcriptional regulator 5
Rv0276 hypothetical protein 5
Rv0307c hypothetical protein 2
Rv0308 integral membrane protein 2
Rv0330c hypothetical protein 1.13
Rv0331 dehydrogenase/reductase 1.13
Rv0338c iron-sulfur-binding reductase 8
Rv0339c transcriptional regulator 3
Rv0340 hypothetical protein 3
Rv0347 membrane protein 19
Rv0348 transcriptional regulator 19
Rv0385 monooxygenase 12
Rv0452 transcriptional regulator 1.10
Rv0472c HTH-type transcriptional regulator 1.26
Rv0474 HTH-type transcriptional regulator 1.27
Rv0485 transcriptional regulator 1.19
Rv0520 -- 5
Rv0523c hypothetical protein 1.1
Rv0674 hypothetical protein 27
Rv0681 transcriptional regulator 9
Rv0759c hypothetical protein 1.38
Rv0793 monooxygenase 1.24
Rv0825c hypothetical protein 5
Rv0826 hypothetical protein 5
Rv0830 S-adenosylmethionine-dependent methyltransferase 2
Rv0842 integral membrane protein 10
Rv0885 hypothetical protein 1.37
Rv0891c hypothetical protein 14
Rv0894 transcriptional regulator 1.30
Rv0941c hypothetical protein 1.38
Rv0942 hypothetical protein 1.38
Rv0947c -- 1.8
Rv0950c hypothetical protein 1.34
Rv1019 transcriptional regulator 13
Rv1024 membrane protein 1.11
Rv1053c -- 1.38
Rv1117 hypothetical protein 4
Rv1167c transcriptional regulator 1.9
Rv1176c hypothetical protein 1.28
Rv1186c hypothetical protein 17
Rv1287 HTH-type transcriptional regulator 23
Rv1290A hypothetical protein 6
Rv1332 transcriptional regulator 1.8
Rv1352 hypothetical protein 1.21
Rv1359 transcriptional regulator 15
Rv1374c hypothetical protein 11
Rv1395 HTH-type transcriptional regulator 1.6
Rv1456c antibiotic ABC transporter permease 1.1
Rv1460 transcriptional regulator 1.12
Rv1489A hypothetical protein 16
Rv1556 HTH-type transcriptional regulator 1.36
Rv1584c phage protein 1.35
Rv1586c phage integrase 1.2
Rv1587c hypothetical protein 1.2
Rv1635c mannosyltransferase 15
Rv1636 iron-regulated universal stress protein 15
Rv1669 hypothetical protein 11
Rv1670 hypothetical protein 11
Rv1674c transcriptional regulator 8
Rv1676 hypothetical protein 11
Rv1773c transcriptional regulator 1.23
Rv1774 oxidoreductase 1.23
Rv1828 HTH-type transcriptional regulator 2
Rv1847 esterase 1.1
Rv1875 hypothetical protein 1.38
Rv1895 zinc-binding alcohol dehydrogenase 1.11
Rv2016 hypothetical protein 31
Rv2017 transcriptional regulator 31
Rv2059 hypothetical protein 4
Rv2132 hypothetical protein 1.15
Rv2148c hypothetical protein 1.35
Rv2204c hypothetical protein 1.16
Rv2205c hypothetical protein 1.16
Rv2323c hypothetical protein 8
Rv2331 hypothetical protein 1.35
Rv2331A hypothetical protein 1.35
Rv2432c hypothetical protein 10
Rv2466c hypothetical protein 1.16
Rv2506 TetR family transcriptional regulator 6
Rv2515c hypothetical protein 18
Rv2639c integral membrane protein 10
Rv2640c ArsR family transcriptional regulator 1.22
Rv2742c arginine-rich protein 2
Rv2779c Lrp/AsnC family transcriptional regulator 1.2
Rv2827c hypothetical protein 16
Rv2912c TetR family HTH-type transcriptional regulator 24
Rv2913c D-amino acid aminohydrolase 24
Rv2990c hypothetical protein 4
Rv2991 hypothetical protein 4
Rv3030 S-adenosylmethionine-dependent methyltransferase 7
Rv3049c monooxygenase 1.37
Rv3050c AsnC family transcriptional regulator 1.37
Rv3058c TetR family transcriptional regulator 21
Rv3094c hypothetical protein 28
Rv3095 HTH-type transcriptional regulator 28
Rv3131 NAD(P)H nitroreductase 1.26
Rv3161c dioxygenase 6
Rv3167c TetR family transcriptional regulator 1.11
Rv3173c TetR/Acr family transcriptional regulator 1.29
Rv3174 short-chain dehydrogenase/reductase 1.29
Rv3177 peroxidase 1.29
Rv3230c stearoyl-CoA 9-desaturase electron transfer partner 13
Rv3269 hypothetical protein 17
Rv3405c HTH-type transcriptional regulator 1.4
Rv3406 dioxygenase 1.4
Rv3463 hypothetical protein 1.7
Rv3479 transmembrane protein 1.6
Rv3531c hypothetical protein 9
Rv3549c short-chain type dehydrogenase/reductase 1.24
Rv3587c membrane protein 1.35
Rv3647c hypothetical protein 3
Rv3660c hypothetical protein 5
Rv3661 hypothetical protein 5
Rv3686c hypothetical protein 1.34
Rv3693 membrane protein 3
Rv3706c proline-rich protein 3
Rv3728 membrane protein 6
Rv3778c aminotransferase 1.32
Rv3779 transmembrane protein 1.32
Rv3832c hypothetical protein 20
Rv3833 AraC family transcriptional regulator 20
Rv3848 transmembrane protein 1.25
Rv3863 alanine-rich protein 1.21
Rv3906c hypothetical protein 18
Rv3922c membrane protein insertion efficiency factor 1.1
scoA succinyl-CoA:3-ketoacid-CoA transferase subunit A 6
sepF cell division protein SepF 1.35
sigC ECF RNA polymerase sigma factor SigC 1.1
sigD ECF RNA polymerase sigma factor SigD 1.14
sigF RNA polymerase sigma factor SigF 1.38
sigK ECF RNA polymerase sigma factor SigK 1.15
sigL ECF RNA polymerase sigma factor SigL 1.16
sigM ECF RNA polymerase sigma factor SigM 18
sirR transcriptional repressor SirR 1.25
ssb single-strand DNA-binding protein 1.7
sucC succinyl-CoA ligase subunit beta 1.10
tgs1 diacyglycerol O-acyltransferase 1.26
trxB1 thioredoxin 1.16
trxC thioredoxin TrxC 1.36
umaA mycolic acid synthase UmaA 6
vapB20 antitoxin VapB20 1.24
vapC20 ribonuclease VapC20 1.24
virS HTH-type transcriptional regulator VirS 29
whiB2 transcriptional regulator WhiB2 1.35
whiB3 redox-responsive transcriptional regulator WhiB3 1.34
whiB6 transcriptional regulator WhiB6 1.32
yidC membrane protein insertase YidC 1.1
zur zinc uptake regulation protein 4