Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (2011, 2012)

Modular genes
Gene Product description NDA class
aac aminoglycoside 2'-N-acetyltransferase 13
accA1 acetyl-/propionyl-CoA carboxylase subunit alpha 4
accD1 acetyl-/propionyl-CoA carboxylase subunit beta 4
adhD alcohol dehydrogenase D 8
alkA bifunctional regulatory protein/DNA repair enzyme AlkA 16
argB acetylglutamate kinase 2
argC N-acetyl-gamma-glutamyl-phoshate reductase 2
argD acetylornithine aminotransferase 2
argF ornithine carbamoyltransferase 2
argG argininosuccinate synthase 2
argH argininosuccinate lyase 2
argJ bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase 2
argR arginine repressor 2
bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase 17
bioB biotin synthetase 17
birA bifunctional biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase 17
bpoC non-heme bromoperoxidase BpoC 4
carA carbamoyl-phosphate synthase small subunit 2
carB carbamoyl-phosphate synthase large subunit 2
ccdA cytochrome C-type biogenesis protein CcdA 6
ccsA cytochrome C-type biogenesis protein CcsA 6
cdsA phosphatidate cytidylyltransferase 2
cfp30B hypothetical protein 24
citE citrate (pro-3S)-lyase subunit beta 4
clpB chaperone protein ClpB 1.12
cmr HTH-type transcriptional regulator Cmr 1.8
cmtR HTH-type transcriptional regulator CmtR 22
csoR copper-sensing transcriptional repressor CsoR 1.1
cspA cold shock protein A 14
ctpG cation transporter ATPase G 22
ctpV copper transporter ATPase V 1.1
cyp143 cytochrome P450 Cyp143 1.3
cysG multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase 1.3
ddn deazaflavin-dependent nitroreductase 6
dnaA chromosomal replication initiator protein DnaA 9
dnaJ1 chaperone protein DnaJ 1.12
dnaK chaperone protein DnaK 1.12
dnaN DNA polymerase III subunit beta 9
drrA daunorubicin ABC transporter ATP-binding protein DrrA 1.4
drrB daunorubicin ABC transporter permease DrrB 1.4
drrC daunorubicin ABC transporter permease DrrC 1.4
dsbF lipoprotein DsbF 6
dus tRNA-dihydrouridine synthase 1.15
echA4 enoyl-CoA hydratase EchA4 16
embA arabinosyltransferase A 18
embB arabinosyltransferase B 18
embC arabinosyltransferase C 18
embR transcriptional regulator EmbR 18
espA ESX-1 secretion-associated protein EspA 5
espC ESX-1 secretion-associated protein EspC 5
espD ESX-1 secretion-associated protein EspD 5
espR ESX-1 transcriptional regulator EspR 5
ethA monooxygenase EthA 26
ethR HTH-type transcriptional repressor EthR 26
fadA3 beta-ketoacyl CoA thiolase FadA 4
fadB5 oxidoreductase FadB 11
fadD13 long chain-fatty-acid--CoA ligase FadD13 8
fadD26 fatty-acid--CoA ligase FadD26 1.4
fadD35 fatty-acid--CoA ligase FadD35 4
fadE19 acyl-CoA dehydrogenase FadE19 4
fadE5 acyl-CoA dehydrogenase FadE5 27
fadE8 acyl-CoA dehydrogenase FadE8 16
fadE9 acyl-CoA dehydrogenase FadE9 20
fbpB diacylglycerol acyltransferase/mycolyltransferase Ag85B 1.9
frr ribosome recycling factor 2
furA ferric uptake regulation protein FurA 11
gap glyceraldehyde 3-phosphate dehydrogenase 1.3
glcB malate synthase 14
glgP glycogen phosphorylase 7
grcC2 polyprenyl-diphosphate synthase GrcC 1.18
grpE protein GrpE 1.12
guaA GMP synthase 9
guaB inosine-5'-monophosphate dehydrogenase 9
gyrA DNA gyrase subunit A 14
gyrB DNA gyrase subunit B 14
hemL glutamate-1-semialdehyde 2,1-aminomutase 6
higA2 transcriptional regulator 1.7
hrcA heat-inducible transcription repressor HrcA 1.18
hsp heat shock protein 1.12
hspR heat shock protein transcriptional repressor HspR 1.12
iniB isoniazid inducible protein IniB 1.9
katG catalase-peroxidase 11
kdpA potassium-transporting ATPase subunit A 19
kdpB potassium-transporting ATPase subunit B 19
kdpC potassium-transporting ATPase subunit C 19
kdpE transcriptional regulator KdpE 19
kgtP -- 21
kstR2 HTH-type transcriptional regulator KstR2 1.13
leuB 3-isopropylmalate dehydrogenase 1.3
lipR acetyl-hydrolase LipR 8
lppE lipoprotein LppE 1.9
lpqY trehalose ABC transporter substrate-binding lipoprotein LpqY 7
lprD lipoprotein LprD 23
lprK Mce family lipoprotein LprK 3
malQ 4-alpha-glucanotransferase 7
mce1A Mce family protein Mce1A 3
mce1B Mce family protein Mce1B 3
mce1C Mce family protein Mce1C 3
mce1D Mce family protein Mce1D 3
mce1F Mce family protein Mce1F 3
mdh malate dehydrogenase 1.8
menC muconate cycloisomerase 4
mmpL12 transmembrane transport protein MmpL12 13
mmsA methylmalonate-semialdehyde dehydrogenase 20
mmsB 3-hydroxyisobutyrate dehydrogenase 20
moxR2 methanol dehydrogenase transcriptional regulator MoxR 1.4
moxR3 methanol dehydrogenase transcriptional regulator MoxR 1.2
mpt53 soluble secreted antigen Mpt53 10
mtrA two component DNA-binding response regulator MtrA 21
mymA FAD-containing monooxygenase MymA 8
nadA quinolinate synthetase A 12
nadB L-aspartate oxidase 12
nadC nicotinate-nucleotide pyrophosphatase 12
nadR transcriptional regulator NadR 12
narL nitrate/nitrite response transcriptional regulator NarL 6
ndh NADH dehydrogenase 5
nirD nitrite reductase small subunit NirD 1.3
nmtR HTH-type transcriptional regulator NmtR 27
nrdF1 ribonucleoside-diphosphate reductase subunit beta NrdF1 5
ogt methylated-DNA--protein-cysteine methyltransferase 16
papA5 phthiocerol/phthiodiolone dimycocerosyl transferase 1.4
PE_PGRS6 PE-PGRS family protein PE_PGRS6 1.8
pgk phosphoglycerate kinase 1.3
pgsA3 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1.12
pknH serine/threonine-protein kinase PknH 18
pknK serine/threonine-protein kinase PknK 7
pks10 chalcone synthase 10
pmt dolichyl-phosphate-mannose--protein mannosyltransferase 5
pncB2 nicotinic acid phosphoribosyltransferase PncB2 12
ppdK pyruvate, phosphate dikinase PpdK 1.3
ppsA phthiocerol synthesis polyketide synthase type I PpsA 1.4
ppsB phthiocerol synthesis polyketide synthase type I PpsB 1.4
ppsC phthiocerol synthesis polyketide synthase type I PpsC 1.4
ppsD phthiocerol synthesis polyketide synthase type I PpsD 1.4
ppsE phthiocerol synthesis polyketide synthase type I PpsE 1.4
pyk pyruvate kinase 1.3
pyrB aspartate carbamoyltransferase 2
pyrC dihydroorotase 2
pyrF orotidine 5'-phosphate decarboxylase 2
pyrH uridylate kinase 2
pyrR bifunctional pyrimidine operon regulatory protein/uracil phosphoribosyltransferase 2
recF DNA replication/repair protein RecF 9
relA bifunctional (p)ppGpp synthase/hydrolase RelA 25
rpfC resuscitation-promoting factor RpfC 1.9
rsdA anti-sigma-D factor RsdA 1.9
rslA anti-sigma-L factor RslA 10
rsmA anti-sigma-M factor RsmA 15
Rv0007 membrane protein 14
Rv0089 methyltransferase 17
Rv0144 transcriptional regulator 3
Rv0175 Mce associated membrane protein 3
Rv0176 Mce associated transmembrane protein 3
Rv0177 Mce associated protein 3
Rv0178 Mce associated membrane protein 3
Rv0250c hypothetical protein 1.12
Rv0260c transcriptional regulator 1.5
Rv0263c hypothetical protein 13
Rv0264c hypothetical protein 13
Rv0302 transcriptional regulator 13
Rv0385 monooxygenase 1.12
Rv0439c dehydrogenase/reductase 1.18
Rv0488 amino-acid transporter 9
Rv0494 HTH-type transcriptional regulator 3
Rv0525 hypothetical protein 6
Rv0526 thioredoxin 6
Rv0528 transmembrane protein 6
Rv0552 hypothetical protein 4
Rv0572c hypothetical protein 3
Rv0574c hypothetical protein 12
Rv0576 transcriptional regulator 24
Rv0674 hypothetical protein 16
Rv0792c transcriptional regulator 20
Rv0818 transcriptional regulator 1.17
Rv0888 hypothetical protein 5
Rv0917 glycine betaine transport integral membrane protein BetP 21
Rv0968 hypothetical protein 1.1
Rv0970 integral membrane protein 1.1
Rv0990c hypothetical protein 1.18
Rv0991c hypothetical protein 1.18
Rv0992c hypothetical protein 1.18
Rv1057 hypothetical protein 28
Rv1075c hypothetical protein 4
Rv1126c hypothetical protein 1.3
Rv1139c hypothetical protein 10
Rv1176c hypothetical protein 17
Rv1234 transmembrane protein 7
Rv1265 hypothetical protein 1.8
Rv1342c hypothetical protein 23
Rv1382 hypothetical protein 2
Rv1676 hypothetical protein 6
Rv1719 transcriptional regulator 4
Rv1815 hypothetical protein 1.9
Rv1816 HTH-type transcriptional regulator 1.9
Rv1817 flavoprotein 5
Rv1882c short-chain type dehydrogenase/reductase 1.9
Rv1883c hypothetical protein 1.9
Rv1885c chorismate mutase 1.9
Rv1907c hypothetical protein 11
Rv1910c hypothetical protein 11
Rv1911c lipoprotein LppC 11
Rv1985c HTH-type transcriptional regulator 9
Rv1990c transcriptional regulator 1.16
Rv1993c hypothetical protein 22
Rv2008c hypothetical protein 5
Rv2017 transcriptional regulator 1.14
Rv2117 hypothetical protein 7
Rv2140c hypothetical protein 2
Rv2141c hypothetical protein 2
Rv2175c DNA-binding protein 1.6
Rv2499c oxidase regulatory-like protein 4
Rv2669 GCN5-like N-acetyltransferase 1.19
Rv2743c transmembrane alanine-rich protein 1.12
Rv2744c alanine-rich protein 1.12
Rv2877c integral membrane protein 10
Rv2879c -- 2
Rv2880c -- 2
Rv2971 oxidoreductase 1.8
Rv3087 diacyglycerol O-acyltransferase 8
Rv322E -- 25
Rv3334 MerR family transcriptional regulator 1.1
Rv3612c hypothetical protein 5
Rv3613c hypothetical protein 5
Rv3678c hypothetical protein 1.21
Rv3833 AraC family transcriptional regulator 1.11
Rv3915 peptidoglycan hydrolase 15
sadH oxidoreductase SadH 8
scoA succinyl-CoA:3-ketoacid-CoA transferase subunit A 4
scoB succinyl-CoA:3-ketoacid-CoA transferase subunit B 4
sigD ECF RNA polymerase sigma factor SigD 1.9
sigJ ECF RNA polymerase sigma factor SigJ 1.10
sigL ECF RNA polymerase sigma factor SigL 10
sugA sugar ABC transporter permease SugA 7
sugB sugar ABC transporter permease SugB 7
sugC sugar ABC transporter ATP-binding protein SugC 7
tgs4 diacyglycerol O-acyltransferase 8
tpiA triosephosphate isomerase 1.3
trcR two component transcriptional regulator TrcR 28
trxB thioredoxin reductase 15
trxC thioredoxin TrxC 15
vapB33 antitoxin VapB33 1.8
vapC33 ribonuclease VapC33 1.8
vapC36 ribonuclease VapC36 5
virS HTH-type transcriptional regulator VirS 8
whiB1 transcriptional regulator WhiB1 15
whiB4 transcriptional regulator WhiB4 1.20
yrbE1A membrane protein 3
yrbE1B membrane protein 3